At Chr. Hansen, we pride ourselves on making the journey from STRAIN TO SOLUTION℧. To achieve this, we follow a series of important steps to understand the science behind바카라 웹사이트. This starts in the laboratory in the preclinical phase, where we explore questions such as what the strain is and what probiotic features it has. Strains that are shown to have desirable properties in the preclinical phase can then be taken into production and tested in human studies, to further understand their role in supporting바카라 웹사이트.바카라 웹사이트
It all starts with carefully selected bacterial strains바카라 웹사이트
Chr. Hansen has a leading collection of bacterial strains that have been isolated or in-licensed from trusted partners. This바카라 웹사이트바카라 웹사이트is the basis for our development of new probiotic products.
New strains are thoroughly characterized using state-of-the-art genomic analysis and laboratory methods, to ensure they are safe. Genome sequencing allows the most accurate identification of the strain and is an essential part of the safety evaluation. Bioinformatic analyses are also used to search strains for the presence of undesirable genes and markers, to confirm whether the strain is a good candidate for the next stage of screening.바카라 웹사이트
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The next step is to establish whether the strain shows promise as a바카라 웹사이트, through a range of tests:바카라 웹사이트바카라 웹사이트
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- Advanced experimental methods are used to test for specific interactions, such as the potential improvement of the intestinal barrier, the specific impact on the immune system, or the production of bioactive molecules.바카라 웹사이트바카라 웹사이트
We can also use bioinformatics to look for the presence of specific genes that are known to be linked to probiotic function. This helps to streamline the process of selecting new probiotic candidates with specific바카라 웹사이트.바카라 웹사이트
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The next step to test how the probiotic will perform under the conditions in the human gastrointestinal (GI) tract. At Chr. Hansen we are using two unique and very advanced models to simulate this: TIM-1 and TIM-2.바카라 웹사이트바카라 웹사이트
TIM-1 is a validated model that simulates the stomach and small intestine, whereas TIM-2, also a validated model, simulates the colon. Both models are highly reflective of the conditions that are known to be important for probiotic survival and function in the human GI tract. This makes the TIM models extremely valuable for studying the survival of probiotics and how formulation affects survival, the production of specific metabolites, or colonization of the large intestine and the benefits of prebiotics.바카라 웹사이트
In certain limited situations, essential animal studies might be used to confirm laboratory findings of certain probiotic candidates. These studies can be used to increase our confidence that the probiotic will have benefits for human studies. Animal studies can also be helpful to suggest what should be measured in human studies, such as markers of a specific functions, and allow analyses of mode of action.바카라 웹사이트
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When a probiotic strain has been selected, the production process is developed in order to ensure a stable and highly viable product. For more information on this stage, see바카라 웹사이트.바카라 웹사이트
Testing for health benefits: Human studies바카라 웹사이트
Many foods and supplements contain live bacteria, but only bacterial strains with a scientifically supported health benefit may correctly be termed바카라 웹사이트. These health benefits can be measured in human studies. These are the primary way that we can find out if a new bacterial strain is safe in people, and that the bacterial strain has benefits in terms of supporting바카라 웹사이트.바카라 웹사이트
In Chr. Hansen we have dedicated specialists in our state-of-the-art Clinical Development Department, who ensure that our research studies are carefully designed, reviewed and completed according to international, ethical and scientific quality standards.바카라 웹사이트 바카라 웹사이트
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We are pioneering바카라 웹사이트바카라 웹사이트to improve health. As part of our commitment, we believe in the need to support ethical, independent scientific research conducted by qualified third-party investigators. These collaborations with external partners are essential to our R&D efforts, and we welcome new partnerships with individual investigators and research teams. The value of these collaborations is key to complementing our own scientific studies in understanding the science behind our strains and exploring potential health benefits for people world-wide.바카라 웹사이트
Chr.
If you would like to hear more about our unique solutions within probiotics, please visit 바카라 웹사이트바카라 웹사이트
